Cleaner Production, Environmental Catalysis

Ph. D in Physical Chemistry

Fudan University, 1993

Tel: 86-21-65642521x802,
Fax: 86-21-65642080

E-mail: jmchen@fudan.ac.cn

Professor Chen joined the Department in 1997. He is presently the Dean of the Department of Environmental Science and Engineering and Deputy Director of Natural Pharmaceuticals at Fudan University. After obtaining his Ph. D. from the Department of Chemistry at Fudan University in July 1993, he started his research and teaching carriers as a faculty in the Chemistry Department of the University. He visited Tokyo University, Osaka University in 1995 as a Research Fellow. He worked with Professors Irving Wender and John W Tierney in the Department of Petroleum and Chemical Engineering in the University of Pittsburgh from March 1996 to April 1997 as a Visiting Professor. In 1999, he was trained in the “Educate the Educators” program organized by United Nations Environmental Program (UNEP) and Lund University in Sweden. He is the editors of Chinese Traditional Patent Medicines and Environmental Pollution & Control.

One of Professor Chen’s research interests is on Aerosol Heterogeneous Chemistry. Atmospheric particles or aerosols play an important role in affecting human health and many aspects of earth environment. Recently, heterogeneous interactions between gaseous molecules and wet or dry aerosol particles’ surfaces have gained considerable interest since they have the potential to significantly alter the gas phase chemistry of the atmosphere. CS₂, COS, DMS and SO₂ are very important atmospheric sulfur-containing compounds. It is well accepted that the atmospheric reaction of CS₂ with HO^• is an important source of COS as well as the dominant sink of CS₂ in the atmosphere. Professor Chen’s team found that the catalytic oxidation of CS₂ over atmospheric particles may be an important way of the conversion from CS₂ to COS close to the Earth’s surface(Environmental Science & Technology, 35, 2543-2547, 2001). Professor Chen is also interested in preparation, characterization and catalytic properties of nonholide solid superacids such as S0₄^2-or S₂0₈^2- promoted ZrO₂, (TiO₂, Fe₂O₃ and oxides) and photo-catalysts like TiO₂ and promoted semiconductors.

His another interest focuses on Cleaner Production. Many Pharmaceutical Facilities involve serious problems of environmental pollution. Huge profits are gained with little effort made on pollution control. For example, Chinese Herb Medicine is very famous all over the world. According to the update reported in 2001, there are over 1300 facilities manufacturing natural products and herbs in China. Most of them are out of GMP or GMPc control causing worse qualities, poor performance and a rapid waste of natural resources. Professor Chen’s team aims to develop cleaner process of natural products with efficacy prep HPLC, CO₂ supercritical fluid extractor (SFE), FT-IR, LC/MS-MS, GC/MS, et. al.. His team succeeds in developing and applying of the Cleaner Process Purifying High Quality Paclitaxel, Solanesol and related natural compounds. The technology has been ventured in Shanghai Fudan Taxusal Corp. Located in Shanghai Zhang-Jiang National High-Tech. Park, and has obtained a huge profit.

Professor Chen was awarded as a Shanghai Distinguished Young Professor in 1999. One paper was awarded as the Worldwide Chinese Distinguished Achievement in 2000. Ministry of Education in 1999 offered one of his achievements as the Second Rank of Advanced Science and Technology. One project was awarded as the First Rank of Advanced Manufacture, Education and Research by Shanghai Science and Technology Committee in 2001. One of his patents was awarded as the Distinguished Patent in Shanghai in 2004. He was also awarded as the Distinguished Graduate Supervisor by Fudan University in 2004. He published over 70 papers, 3 books and 7 Chinese Invention Patents.

1. Wu HB, Wang X, Chen JM.Photooxidation of carbonyl sulfide in the presence of the typical oxides in atmospheric aerosol SCIENCE IN CHINA SERIES B-CHEMISTRY 48 (1): 31-37 FEB 2005

2. Lin HX, Jiang Y, Chen JM, et al. Synthesis and crystal structure of 2-debenzoyl and 4-deacetyl 1-deoxybaccatin VI derivatives JOURNAL OF MOLECULAR STRUCTURE 738 (1-3): 59-65 MAR 14 2005

3. Jiang Y, Lin HX, Chen JM, et al. Crystallographic determination of stereochemistry of biologically active 2 '',3 ''-dibromo-7-epi-10-deacetylcaphalomannine (vol 15, pg 839, 2005) BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 15 (6): 1757-1757 MAR 15 2005

4. Jiang Y, Lin HX, Li M, Chen JM et al. Preparation and evaluation of new brominated paclitaxel analogues JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 7 (3): 231-236 JUN 2005

5. Wu HB, Wang X, Chen JM, et al. Mechanism of the heterogeneous reaction of carbonyl sulfide with typical components of atmospheric aerosol CHINESE SCIENCE BULLETIN 49 (12): 1231-1235 JUN 2004

6. Xue HX, Song GX, Wang L, et al. Studies of n-pentane reaction on tungsten carbides promoted S2O82-/ZrO2 solid superacid catalysts ACTA CHIMICA SINICA 61 (2): 208-212 FEB 2003

7. Wang L, Zhang F, Chen JM Catalytic oxidation of CS2 over atmospheric particles and oxide catalysts SCIENCE IN CHINA SERIES B-CHEMISTRY 44 (6): 587-595 DEC 2001

8. Wang L, Zhang F, Chen JM Carbonyl sulfide derived from catalytic oxidation of carbon disulfide over atmospheric particles ENVIRONMENTAL SCIENCE & TECHNOLOGY 35 (12): 2543-2547 JUN 15 2001

9. Xue J, Chen JM, Zhang L, et al. Large-scale process for high purity taxol from bark extract of Taxus yunnanesis JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES 23 (16): 2499-2512 2000

10. Zhang L, Wang L, Chen JM Studies of peroxodisulfated zirconia solid superacid CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 21 (1): 116-119 JAN 2000

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